The Center for Bioinformatics is pleased to announce the arrival of its newest faculty member, Dr. Eric J. Deeds. Dr. Deeds is an expert in the development of mathematical and computational models of biological systems. He is excited to apply this expertise to studying the assembly of macromolecular complexes. Dr. Deeds plans to use these modeling efforts to provide insight into biological assembly mechanisms, to discover novel ways to inhibit assembly processes, and to provide general techniques for the design of novel macromolecular structures that will self-assemble efficiently.
Dr. Deeds received his Ph.D. from the Department of Molecular and Cellular Biology at Harvard University in 2005. His graduate research in theoretical and computational biophysics was conducted in the lab of Eugene Shakhnovich, where he studied the evolution of protein structure, explored the dynamics of protein folding, and developed simple physical models for topology and specificity in Protein-Protein Interaction (PPI) Networks.
Dr. Deeds completed his postdoctoral fellowship in the lab of Walter Fontana in the Department of Systems Biology at Harvard Medical School. In the Fontana lab, he helped to develop and apply a novel rule- and agent-based method for modeling the dynamics of protein interaction and signaling networks. He used these techniques to perform the first large-scale simulations of the dynamics of an entire PPI network. He also applied these methods to the dynamics of assembly of ring-like protein complexes, work that he is excited to extend in his new lab.
Dr. Deeds joins the Center at the rank of assistant professor, with a joint appointment in the Department of Molecular Biosciences.